Link between diabetes and bacteria in the gut
Six groups of bacteria in the gut microbiome have now been identified and are associated with an increased risk of developing type 2 diabetes. Fortunately, these bacteria appear to be at least partially linked to diet quality.
In a recent study involving experts from University of Turku in Finland, six groups of bacteria from the Lachnospiraceae family and their close relatives have been shown to be able to predict the onset of type 2 diabetes.
The results, published in the English-language journal Diabetes Care, show:
- Particular types of bacteria in the gut microbiota increase the risk of type 2 diabetes.
- These bacteria can be affected by food.
- A healthy lifestyle can protect against diabetes.
- Influencing gut flora could lead to more effective diabetes treatments.
Type 2 diabetes continues to rise worldwide
Type 2 diabetes – also known as adult-onset diabetes – is on the rise worldwide. The disease has a significant impact on the quality of life of those affected and results in high costs for health systems.
Protect yourself from diabetes through a healthy lifestyle
However, it would be possible to prevent the onset of the disease if the signs of type 2 diabetes are recognized in time and if countermeasures such as a change in diet are taken immediately, the team explains.
diabetes risk factors
Several risk factors for type 2 diabetes have already been identified in various studies in the past. According to the researchers, these include, for example, genetics, lifestyle and environmental factors.
The composition of the gut microbiome (gut flora) has also been linked to type 2 diabetes. However, previous studies have mainly focused on the differences between healthy people and people who already have type 2 diabetes.
Risk of diabetes due to intestinal bacteria?
In the study, the team investigated whether certain compositions of the gut microbiome are associated with an increased risk of developing type 2 diabetes.
For the study, stool samples from a Finnish population cohort called FINRISK 2002 were evaluated. In addition to collecting samples, health data was also collected from 5,572 participants. Researchers determined disease occurrence by evaluating health record data over a 16-year period.
Microbial biomarkers identified for diabetes
Data analysis identified specific microbial biomarkers associated with the development of diabetes in participants.
According to the author of the study, the microbes identified could be clearly linked to the occurrence of diseases Matt Ruuskanen from University of Turku. Indications of a link between the types of bacteria and the occurrence of type 2 diabetes and various other metabolic diseases had already been suspected before.
Influence of diet on bacteria in the gut
These types of bacteria appear to be at least partially linked to diet quality, study author points out Pande Erawijantari from University of Turku in a press release.
The results confirm previous hypotheses about associations between adult diabetes, dietary habits and metabolic diseases, which are likely influenced by the gut microbiome, according to the study author.
The current study helps develop a better understanding of type 2 diabetes risk factors and the gut microbiome could potentially be used to improve disease prediction and discover new therapeutic targets for diabetes. (like)
Author and source information
This text corresponds to the requirements of the specialized medical literature, medical guidelines and current studies and has been verified by health professionals.
- Matti O. Ruuskanen, Pande P. Erawijantari, Aki S. Havulinna, Yang Liu, Guillaume Méric, et al. : Gut microbiome composition is predictive of type 2 diabetes incidence in a population cohort of 5,572 Finnish adults; in: Diabetes Care (published January 31, 2022), Diabetes Care
- University of Turku: Gut Microbiome Composition Predicts Onset of Type 2 Diabetes (Published 2022-02-16), University of Turku
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot substitute a visit to the doctor.